Pharmacological Management, Continued
- Nonbenzodiazepine hypnotics (cont.).
- Suvorexant (Belsomra).
- Dosage range: 10-20 mg at bedtime.
- FDA indication for insomnia (sleep initiation and maintenance).
- Antidepressants (used for sedating properties).
- Amitriptyline (Elavil).
- Dosage range: 50-300 mg at bedtime.
- Used off-label for insomnia.
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- Doxepin (Silenor).
- Dosage range: 3-6 mg at bedtime.
- FDA indication for insomnia (sleep maintenance).
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- Mirtazapine (Remeron).
- Dosage range: 15-45 mg at bedtime.
- Used off-label for insomnia.
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- Trazodone (Desyrel).
- Dosage range: 25-200 mg at bedtime.
- Used off-label for insomnia.
*Benzodiazepines and hypnotics should not be used in those with obstructive sleep apnea*
Puzantian & Carlat, 2020