D35 – 3.3 Pharmacological Management, Continued

Pharmacological Management, Continued

  • Nonbenzodiazepine hypnotics (cont.).
    • Suvorexant (Belsomra).
      • Dosage range: 10-20 mg at bedtime.
      • FDA indication for insomnia (sleep initiation and maintenance).
  • Antidepressants (used for sedating properties).
    • Amitriptyline (Elavil).
      • Dosage range: 50-300 mg at bedtime.
      • Used off-label for insomnia.
    • Doxepin (Silenor).
      • Dosage range: 3-6 mg at bedtime.
      • FDA indication for insomnia (sleep maintenance).
    • Mirtazapine (Remeron).
      • Dosage range: 15-45 mg at bedtime.
      • Used off-label for insomnia.
    • Trazodone (Desyrel).
      • Dosage range: 25-200 mg at bedtime.
      • Used off-label for insomnia.

*Benzodiazepines and hypnotics should not be used in those with obstructive sleep apnea*

Puzantian & Carlat, 2020