D29 – 4.3 Other Treatments for TRD

Other Treatments for TRD

  • Electroconvulsive Therapy (ECT)
    • Given under anesthesia.
    • Electric impulses pass through the brain and induce a brief seizure. This activity is theorized to activate the brain and brain chemicals in a way they relieve depression.
    • Commonly used for severe major depressive disorder that has not responded to other treatments.
    • Substantial improvement in about 80% of patients.
  • Transcranial Magnetic Stimulation (TMS)
    • Uses a magnetic field to stimulate the nerves in the brain.
    • It is noninvasive.
    • FDA approved from depression that has not responded to 1 prior medication trial.
    • Improvement noted in about 60% of patients.
(American Psychiatric Association, 2019; Carlat & Puzantian, 2020)