Demo Chapter – Pharmacological Treatments, Continued

Pharmacological Treatments, Continued (4, 5, 6)

Zolpidem:

• Non-benzodiazepine agonist of GABA-A receptor in the brain.
• Alternative to lorazepam.

• Dose, route, and frequency:
  • 10 mg orally given once.
  • Max dose 40mg/day.

• Length of therapy:
  • The dose is generally given once.
  • Administration can be repeated on a subsequent day.

• Response Rate:
  • Symptom improvement occurs 15-30 minutes after administration and lasts 2-5 hours.
  • It produces a prompt response and a 50% reduction of symptoms.

(4) Bartolommei, N., Lattanzi, L., Callari, A., Cosentino, L., Luchini, F., & Mauri, M. (2012). Catatonia: a critical review and therapeutic recommendations. Journal of psychopathology, 18, p. 235.

(5) Moore, D. P. & Jefferson, J. W. (2004). Catatonia. In handbook of medical psychiatry, 2nd ed. St. Louis, mo: mosby, pp. 292-293.

(6) American psychiatric association practice guideline for the treatment of patients with schizophrenia, second edition, 2004 http://www.Psych.Org/mainmenu/psychiatricpractice/Practiceguidelines_1.Aspx